How chromosomes shrink to fit

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How chromosomes shrink to fit

Cells in an early embryo need to downsize their DNA. Ladouceur et al. show that a cell’s size and the size of its nucleus determine how small its chromosomes become (1). Like someone who’s moved from a house to an apartment, cells in an early embryo run into space limitations. The embryo remains the same size for its fi rst few divisions, so the cells have to become much smaller, shrinking by a...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2015

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb.2095if